Serum Response Factor (SRF) Peptide
SRF
Reactivité: Humain, Souris
Hôte: Synthetic
BP, ChIP, WB
N° du produit ABIN984414
Aperçu rapide pour Serum Response Factor (SRF) Peptide (ABIN984414)
Antigène
SRF
(Serum Response Factor (SRF))
Origine
Humain, Souris
Source
Synthetic
Application
Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SRF antibody (Catalog #: P100866_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SRF (Serum Response Factor (SRF))
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Sujet
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SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
Alias Symbols: MCM1
Protein Interaction Partner: FHL1,FHL2,FHL3,FHL5,FOS,FOSL1,NFYA,ATF6,BARX2,CAMK2A,CASP3,CASP6,CASP7,CASP8,CASP9,CEBPB,CREB1,CREBBP,CRIP2,CSNK2A1,ELK1,ELK4,ETV4,FHL1,FHL2,FHL3,FHL5,FLI1,GATA4,GTF2F1,GTF2I,HMGA1,HOPX,MAPKAPK2,MINPP1,MKL1,MKL2,MYOCD,MYOD1,MYOG,NCOA1,NCOR2,NFYA,NKX2-3,NKX2-5,NKX3-1,OGT,PML,PRKDC,PRRX1,PYCARD,RELA,RPS6KA1,RXRA,RXRG,SRC,SRF,SRFBP1,SSRP1,TCF3,TEAD1,ASCC1,ASCC2,ASCC3,ATF6,CD63,CEBPB,CREBBP,ELK1,ELK4,FLI1,GATA4,GTF2F1,GTF2I,Gata2,Gata4,Gata6,Hmga1,Hmga2,MKL1,MKL2,MYOCD,MYOG,Mkl1,Mkl2,Myocd,NCOA6,NCOR2,NFYA,NKX3-1,Nkx2-5,PML,RARG,REL,RELA,RXRG,SMARCA4,SP1,SRC,SSRP1,Ssrp1,TEAD1
Protein Size: 508 -
Poids moléculaire
- 52 kDa
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ID gène
- 6722
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NCBI Accession
- NM_003131, NP_003122
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UniProt
- P11831
Antigène
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